The Audacious Project commitment will support the development of new classes of prescription antibiotics to treat the world’s deadliest bacterial pathogens.
Housed at TED and supported by leading social effect advisor The Bridgespan Group, The Audacious Project is a collective financing effort that’s catalyzing social effect on a grand scale by convening funders and social business owners, with the goal of supporting bold services to the world’s most immediate difficulties.
Amongst this year’s thoroughly chosen change-makers is Jim Collins and a team at MIT’s Abdul Latif Jameel Clinic for Machine Learning in Health (Jameel Clinic), including co-principal investigator Regina Barzilay. The financing provided through The Audacious Project will support the response to the antibiotic resistance crisis through the advancement of brand-new classes of prescription antibiotics to safeguard patients versus a few of the world’s most dangerous bacterial pathogens.
” The work of Jim Collins and his colleagues is more relevant now than ever before,” states Anantha P. Chandrakasan, dean of the MIT School of Engineering and the Vannevar Bush Professor of Electrical Engineering and Computer Science. “We are grateful for the commitment from The Audacious Project and its factors, to both support and cultivate the research study around AI and drug discovery, and to join our efforts in the School of Engineering to realize the prospective global effect of this unbelievable work.”
Collins’ and Barzilay’s Antibiotics-AI Project seeks to produce the very first brand-new classes of antibiotics society has seen in 3 years, by contacting an interdisciplinary group of world-class bioengineers, microbiologists, computer system researchers, and chemists.
Collins is the Termeer Professor of Medical Engineering and Science in MIT’s Institute for Medical Engineering and Science (IMES) and the Department of Biological Engineering, professors co-lead of Jameel Clinic, professors lead of the MIT-Takeda Program, and a member of the Harvard-MIT Health Sciences and Technology faculty. He is likewise a core founding faculty member of the Wyss Institute for Biologically Inspired Engineering at Harvard University and an Institute member of the Broad Institute of MIT and Harvard.
Barzilay is the Delta Electronics Professor in MIT’s Department of Electrical Engineering and Computer technology, professors co-lead of Jameel Center, and a member of the Computer technology and Expert System Lab at MIT.
Previously this year, Collins and Barzilay together with Tommi Jaakkola, Thomas Siebel Professor of Electrical Engineering and Computer Technology, and the Institute for Data, Systems, and Society, and postdoc Jonathan Stokes were part of a research team that successfully utilized a deep-learning design to recognize a brand-new antibiotic. Over the next seven years, The Audacious Job’s commitment will support Collins and Barzilay as they continue to use the same procedure to rapidly explore over a billion molecules to identify and design unique prescription antibiotics.