A new low-priced diagnostic test for coronavirus illness 2019 (COVID-19) rapidly provides precise results without the requirement for sophisticated devices, according to a research study published August 27 2020 in the open-access journal PLOS Pathogens by Teng Xu of the Vision Medicals Center for Transmittable Illness, Tieying Hou of the Guangdong Academy of Medical Sciences, Bing Gu of the Affiliated Medical Facility of Xuzhou Medical University, Jianwei Wang of the Chinese Academy of Medical Sciences and Peking Union Medical College, and associates.
The surging demand for quick screening and recognition of COVID-19 positions excellent diagnostic challenges. Metagenomic next-generation sequencing (mNGS) and reverse-transcription PCR (RT-PCR) have actually been the most typically utilized molecular approaches for detecting COVID-19, however each has its own constraints.
In the new study, the researchers developed an alternative COVID-19 test by leveraging CRISPR-based innovation, which has been commonly utilized in current years for gene editing. The assay, named CRISPR-COVID, enables high-throughput detection of severe intense respiratory syndrome coronavirus 2 (SARS-CoV-2)– the infection that triggers COVID-19
The authors keep in mind, “In this research study, we developed an isothermal, CRISPR-based diagnostic for COVID-19 with near single-copy sensitivity.” and “We showed a CRISPR-based assay for COVID-19 that provided shorter turn-around time and great diagnostic worth, even in under-resourced settings without the need of thermal cyclers.”
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